Jeff Radwell - Genetic and Epigenetic Foundations, Molecular Basis, and Mechanistic Pathways of Chronic Inflammation-Driven Tumorigenesis: Targeting NF-κB and STAT3 Signaling

Selected Works

Nonfiction

A history of resistance

Genetic and Epigenetic Foundations, Molecular Basis, and Mechanistic Pathways of Chronic Inflammation-Driven Tumorigenesis: Targeting NF-κB and STAT3 Signaling

This comprehensive volume unpacks the intricate molecular mechanisms linking inflammation and oncogenesis, from oxidative DNA damage to epigenetic modifications that rewire cellular fate.

The Immunogenome: A Blueprint for Immunity, Disease, and Longevity

Your immune system is as unique as your DNA, but what if we could decode the genetic blueprint that governs these immune response, and even modify it?

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Genetic and Epigenetic Foundations, Molecular Basis, and Mechanistic Pathways of Chronic Inflammation-Driven Tumorigenesis: Targeting NF-κB and STAT3 Signaling

Chronic inflammation is a silent yet powerful driver of cancer, altering genetic and epigenetic landscapes to promote tumor progression, immune evasion, and therapy resistance. This comprehensive volume unpacks the intricate molecular mechanisms linking inflammation and oncogenesis, from oxidative DNA damage to epigenetic modifications that rewire cellular fate.

Examining key pathways such as NF-κB, STAT3, and TGF-β, this text provides a rigorous yet accessible analysis of inflammation-driven tumorigenesis. With a focus on genetic mutations, histone modifications, and therapeutic targets, it bridges fundamental research with clinical implications, offering insights into novel intervention strategies.